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Bone marrow transplantation and organ transplants in general have been found to introduce foreign DNA into patients.Gene therapy is defined by the precision of the procedure and the intention of direct therapeutic effects.

In this experiment, as in most molecular biology techniques, a control must be used to ensure successful experimentation.

In molecular biology, procedures and technologies are continually being developed and older technologies abandoned.

For example, before the advent of DNA gel electrophoresis (agarose or polyacrylamide), the size of DNA molecules was typically determined by rate sedimentation in sucrose gradients, a slow and labor-intensive technique requiring expensive instrumentation; prior to sucrose gradients, viscometry was used.

Aside from their historical interest, it is often worth knowing about older technology, as it is occasionally useful to solve another new problem for which the newer technique is inappropriate rapeutic delivery of nucleic acid polymers into a patient's cells as a drug to treat disease.

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